北海道大学 大学院 保健科学研究院 健康イノベーションセンター 高度脂質分析ラボラトリー/細胞代謝化学研究室

研究実績/学会/総説

最近の論文

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Zhao Y, Chen Z, Wu Y, Tsukui T, Ma X, Zhang X, Chiba H, Hui S-P (2019) Separating and Profiling Phosphatidylcholines and Triglycerides from Single Cellular Lipid Droplet by In-Tip Solvent Microextraction Mass Spectrometry. Anal. Chem. 91(7), 4466. doi: 10.1021/acs.analchem.8b05122

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Yamamoto, Y.; Sakurai, T.; Chen, Z.; Furukawa, T.; Gowda, S. G. B.; Wu, Y.; Nouso, K.; Fujii, Y.; Yoshikawa, Y.; Chiba, H.; et al. Analysis of Serum Lysophosphatidylethanolamine Levels in Patients with Non-Alcoholic Fatty Liver Disease by Liquid Chromatography-Tandem Mass Spectrometry. Anal Bioanal Chem 2020 (Accepted)

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Yamamoto Y, Furukawa T, Takeda S, Kashida H, Chiba H, Hui S-P (2018) Examining the effect of regioisomerism on the physico-chemical properties of lysophosphatidylethanolamine-containing liposomes using fluoro probes. Chem Phys Lipids 216:9–16. doi: 10.1016/j.chemphyslip.2018.08.001

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Wu, Y.*; Chen, Z.*; Darwish, W. S.; Terada, K.; Chiba, H.; Hui, S.-P. (2019) Choline and Ethanolamine Plasmalogens Prevent Lead-Induced Cytotoxicity and Lipid Oxidation in HepG2 Cells. J. Agric. Food Chem. 67 (27), 7716–7725. doi: 10.1021/acs.jafc.9b02485 *contributed equally.

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Wu Y, Chen Z, Chiba H, Hui S-P. Plasmalogen fingerprint alteration and content reduction in beef during boiling, roasting, and frying. Food Chem 2020, 322:126764.

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Tsukui, T.; Chen, Z.; Fuda, H.; Furukawa, T.; Oura, K.; Sakurai, T.; Hui, S.-P.; Chiba, H. (2019) Novel Fluorescence-Based Method to Characterize the Antioxidative Effects of Food Metabolites on Lipid Droplets in Cultured Hepatocytes. J. Agric. Food Chem. 67 (35), 9934-9941. doi: acs.jafc.9b02081.

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Takeda S., Mukasa K., Chiba H., Hui S.-P. (2019) Interaction between LDL-mimetic liposomes and acid-treated carbon nanotube electrode during Cu2+-mediated oxidation. Biochemical and Biophysical Research Communications 513(1), 275. doi: 10.1016/j.bbrc.2019.03.106.

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Takahashi Y, Ito Y, Sakurai T, Wada N, Nagasaka A, Fujikawa M, Chiba H, Hui S-P (2018) A two-step homogeneous assay for apolipoprotein E-containing high-density lipoprotein-cholesterol. Ann Clin Biochem Int J Lab Med 000456321879521. doi: 10.1177/0004563218795212

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Siddabasave Gowda B. Gowda, Hirotoshi Fuda, Takayuki Tsukui, Hitoshi Chiba, Shu-Ping Hui. Discovery of Eicosapentaenoic Acid Esters of Hydroxy Fatty Acids as Potent Antioxidants via Activation of Keap1-Nrf2 Signaling. Antioxidants 2020, 9 (5), 397.

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Siddabasave Gowda B. Gowda, Chongsheng Liang, Divyavani Gowda, Fengjue Hou, Kentaro Kawakami, Satoru Fukiya, Atsushi Yokota, Hitoshi Chiba, Shu-Ping Hui. Identification of short chain fatty acid esters of hydroxy fatty acid (SFAHFA) in murine model by nontargeted analysis using UHPLC/ LTQ Orbitrap MS. Rapid Communications in Mass Spectrometry (Accepted)